生薬の生物活性成分に関する研究--センブリエキス,SwertiamarinおよびGentianineの薬理作用 [in Japanese] Biologically active principles of crude drugs : pharmacological actions of Swertia japonica extracts, swertiamarin and gentianine [in Japanese]
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The pharmacological effect of a methanolic extract of Swertia japonica, swertiamarin being the main secoiridoid glucoside of this herb and gentianine obtained from swertiamarin in aqueous ammonia, were investigated in mice and rats. Gentianine was found to exert depression of the central nervous system and anti-ulcerogenic action, as well as inhibitory action against gastric secretion, whereas the others had no appreciable action.
- Journal of the Pharmaceutical Society of Japan
Journal of the Pharmaceutical Society of Japan 98(11), p1446-1451, 1978-11
The Pharmaceutical Society of Japan