せんぶりSwertia japonica MAKINOより得られる人工塩基について Artificial Bases from Swertia japonica MAKINO
The detailed investigation on the bases of Swertia japonica MAKINO was carried out. Extraction of the plant with chloroform using ammonia as usual gave, gentianine and a base of m.p. 129.5〜130°. The structure of the latter was now elucidated. On the other hand, however, the extraction with methanol in the absence of ammonia as well as the treatment with methylamine gave none of these compounds. Thus, an evidence that both substances must be the artifacts produced during the extraction process was presented.
薬学雑誌 86(12), 1202-1204, 1966-12