Galanthamine Chemistry. V. Formation of Hydroxyapogalanthamine from Galanthaminone and the Synthesis of its Trimethyl Ether.

Access this Article

Search this Article

Author(s)

Abstract

Treatment of galanthaminone with hydriodic acid gave hydroxyapogalanthamine, the structure of which has been elucidated by degradation to the known diphenic acid (IV). The trimethyl ether of hydroxyapogalanthamine has been synthesized by two methods, confirming the structure of this important transformation product of galanthaminone. Based on this and other chemical evidence it has been concluded that galanthamine is represented by formula (III).

Journal

  • Chemical and Pharmaceutical Bulletin

    Chemical and Pharmaceutical Bulletin 12(6), 696-705, 1964

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    110003661471
  • NII NACSIS-CAT ID (NCID)
    AA00602100
  • Text Lang
    ENG
  • ISSN
    0009-2363
  • Data Source
    NII-ELS  J-STAGE 
Page Top