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The physiological activities of streptothricin antibiotics were investigated, taking racemomycin-D as a representative of the group. It was found that racemomycin-D has insecticidal activity, fish-toxicity and inhibitory activity on plant growth. Firstly, racemomycin-D showed a weak but broad-spectrum insecticidal activity against the adults of Blattella germanica, Musca domestica, Nilaparvata lugens, Laodelphax striatella, and Plutella xylostella. A rather strong insecticidal effect on Culex pipiens molestus larvae was found, with mortalities of 90% and 15% at 10 ppm and 2 ppm, respectively. Though racemomycin-D showed no insecticidal effect against the larvae of Spodoptera litura, it showed inhibitory activity on feeding at a concentration of 300 ppm. Secondly, racemomycin-D was toxic to all the fish species examined, i. e., Misgurnus anguillicaudatus, Carassius auratus, and Oriziae latipes. Among these, racemomycin-D showed particularly strong toxicity against C. auratus with a TLm of 3.7 ppm (after 48 hr). Thirdly, racemomycin-D showed strong inhibitory activity on the growth of Brassica campestris L. subsp. Napus Hook fil et Anders var. nippo-okifera, Arctium Lappa L., Petrocelium sativum, and Raphanus sativus L. var. acanthiformis at a concentration of 500 ppm (with an inhibitory ratio of 0.1, relative to 1.0 for the control group).
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 28 (10), 2884-2891, 1980
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679138926976
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- NII論文ID
- 110003662394
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- NII書誌ID
- AA00602100
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- COI
- 1:CAS:528:DyaL3MXis1WisA%3D%3D
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- ISSN
- 13475223
- 00092363
- http://id.crossref.org/issn/00092363
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- PubMed
- 6256090
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可