Risk Factors for Liver Dysfunction in Middle Aged Men based on Four Year Health Examination Data.

• TAJIMA Kumiko

  Department of Public Health, Gunma University School of Medicine

• TAKEUCHI Kazuo

  Gunma Prefectural College of Health Sciences

• SUZUKI Shosuke

  Department of Public Health, Gunma University School of Medicine

書誌事項

タイトル別名

• Risk Factors for Liver Dysfunction in M

抄録

Risk Factors for Liver Dysfunction in Middle Aged Men based on Four Year Health Examination Data: Kumiko TAJIMA, et al. Department of Public Health, Gunma University School of Medicine-In order to develop a better lifestyle improvement program, the relationship between lifestyle and changes in liver function were compared through data-linkage of a self-administered questionnaire to the results of annual health examinations over 4 years. In this study, 2, 511 male subjects aged 40-69 yr were asked to fill in the questionnaire. Of these, 824 subjects had a health examination in 1993. Two hundred and twenty-eight of these remained within the normal range in liver function tests (LFT) in each of annual health examinations between 1994 and 1996, whereas 63 had worsened LFT results after the initial examination and were therefore called the decreased liver function (DLF) group. Controls age-matched to the DLF group were chosen from the normal liver function group. Discriminant function analysis was carried out to identify the differences between the DLF group and the control group. The independent variables were selected from the variables which showed significant differences in the univariate analysis, considering multicollinearity. The independent variables used for the discriminant analysis were therefore alcohol consumption, diastolic blood pressure (DBP), BMI and “aggression” by THI. The Wilks'' Lambda value was 0.787 (p value=0.0001). The overall correct identification rate in the discriminant analysis was 75.0%. The results of the present study suggest that men who are heavy drinkers, hypertensive, obese and aggressive had a high risk of developing liver dysfunction within a few years, even if their LFT values were within normal limits in any single year.

収録刊行物

• ｊｏｕｒｎａｌ　ｏｆ　Ｏｃｃｕｐａｔｉｏｎａｌ　Ｈｅａｌｔｈ

  ｊｏｕｒｎａｌ　ｏｆ　Ｏｃｃｕｐａｔｉｏｎａｌ　Ｈｅａｌｔｈ 40 (4), 339-344, 1998

  公益社団法人 日本産業衛生学会

キーワード

• Liver function
• Middle aged man
• Risk factor
• Lifestyle
• Health examination
• Longitudinal study

詳細情報

• CRID: 1390282679430832256
• NII論文ID: 130003527384
• NII論文ID: 110003723025
• NII書誌ID: AA11090645
• DOI: 10.1539/joh.40.339
• ISSN: 13489585
• ISSN: 13419145
• NDL書誌ID: 4624061
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4624061
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1539%2Fjoh.40.339
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1539/joh.40.339
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
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