卵巣摘出が成熟ラット下顎関節突起に及ぼす影響に関する軟X線写真画像解析  [in Japanese] Binary Image Analysis of Bone Marrow Area with Soft X-Ray Photographs in Mandibular Condyle of Ovariectomized Rats  [in Japanese]

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Author(s)

    • 田中 みか子 TANAKA Mikako
    • 新潟大学歯学部歯科補綴学第一講座 Department of Removable Prosthodontics, School of Dentistry, Niigata University
    • 江〓 貞一 EJIRI Sadakazu
    • 新潟大学歯学部口腔解剖学第一講座 1st Department of Oral Anatomy, School of Dentistry, Niigata University
    • 河野 正司 KOHNO Shoji
    • 新潟大学歯学部歯科補綴学第一講座 Department of Removable Prosthodontics, School of Dentistry, Niigata University
    • 小澤 英浩 OZAWA Hidehiro
    • 新潟大学歯学部口腔解剖学第一講座 1st Department of Oral Anatomy, School of Dentistry, Niigata University

Abstract

近年,日本では急速に高齢化社会を迎えつつあり,閉経後骨粗顆症は,歯科臨床領域においても注目されている.特に顎関節部に対する骨粗蛎症の影響を明らかにすることは,骨粗耘症と,顎関節症をはじめとする咀咽機能の低下との間に関連性が考えられることから重要である.そこで本研究では卵巣摘出ラットを用いて,エストロゲン欠乏が下顎関節突起に及ぼす影響を明らかにするため,骨密度測定および軟X線写真の2値化画像解析を行った.画像解析の結果から,エス1・ロゲン欠乏により下顎関節突起の骨形成が抑制されることが明らかとなり,歯科領域においても閉経後骨粗胤症に対する注意が必要であることを提唱している.

The advanced age society will be coming up soon in our country. Postmenopausal osteoporosis is a major health issue and a matter of concern in the dental clinical field. It is important to find out its effect on the temporomandibular joint in relation to masticatory function and temporomandibular disorders of elderly people. In this study, an attempt was made to determine if estrogen deficiency affect the mandibular condyle.<BR>Seventy-two adult female Fischer rats were used. Half of them were ovariectomized bilaterally (OVX) and the other half were subjected to sham surgery (Sham). Seven, 14, 30, and 60 days after surgery, 8 animals in each group were sacrificed and mandibles were carefully removed. The bone marrow area was assessed with binary image of soft X-ray photographs, and the bone mineral density (BMD) was measured by DEXA (Dual Energy X-ray Absorptiometry).<BR>The binary imaged bone marrow area of the OVX group was significantly larger than that of the Sham group at 14, 30, and 60 days. Estrogen deficiency suppressed the reduction of the bone marrow area that occurs with aging in the rat mandibular condyle. However, no significant difference of BMD was found between the OVX and Sham groups, probably because cortical bone overshadowed the changes of trabecular bone.

Journal

  • Nihon Hotetsu Shika Gakkai Zasshi

    Nihon Hotetsu Shika Gakkai Zasshi 40(4), 806-811, 1996-08-01

    The Japan Prosthodontic Society

References:  69

Cited by:  4

Codes

  • NII Article ID (NAID)
    110003858510
  • NII NACSIS-CAT ID (NCID)
    AN00197911
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03895386
  • Data Source
    CJP  CJPref  NII-ELS  J-STAGE 
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