血清中クレアチンキナーゼ活性値およびアイソザイムパターンに対する腸管中にクレアチンキナーゼの寄与

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  • The contribution of intestinal creatine kinase to serum creatine kinase activity and its isoenzymes in dogs.
  • 血清中クレアチンキナーゼ活性値およびアイソザイムパターンに対する腸管中のクレアチンキナーゼの寄与〔英文〕
  • ケッセイチュウ クレアチンキナーゼ カッセイチ オヨビ アイソザイム パターン

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To investigate the contribution of intestinal creatine kinase (CK) to serum CK activity and its isoenzymes, neostigmine, an anticholinesterase agent, was injected into 8 dogs to stimulate intestinal peristalsis. Serum CK activity was increased 3 hr after injection and had a similar isoenzyme pattern to that of intestine. CK activity decreased to normal range within 24 or 48 hr. Serum CK activities did not change in dogs injected both with neostigmine and stropine, or only atropine. Thus hyperperistalsis of the interstine might increase the activity of serum CK and altere its isoenzyme pattern. Intestinal CK could contribute to serum CK activity and its isoenzyme pattern.

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