糖尿病ハタネズミにおけるグルコキナーゼ・ヘキソキナーゼ活性の変化

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タイトル別名
  • Changes of glucokinase and hexokinase activities in the diabetic Microtus arvalis pallas.
  • 糖尿病ハタネズミにおけるグリコキナーゼ・ヘキソキナーゼ活性の変化(短報)〔英文〕
  • トウニョウビョウ ハタネズミ ニ オケル グリコ キナーゼ ヘキソ キナーゼ

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抄録

In Microtus species, diabetes was induced easily by feeding with low fiber and high concentrate diet. It was considered to be caused of their characteristic as herbivore that the renal threshold for glucose or glycolytic enzymes (GK, HK) activities were very low. In the diabetic voles, the glycolytic enzymes activities controlled by insulin changed greatly with the progress of the disease. So, Microtus species is considered to be useful as an animal model of the disorder of glucose metabolism in herbivore.

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