A Cross‐Sectional Study on the Relationship of Job Stress with Natural Killer Cell Activity and Natural Killer Cell Subsets among Healthy Nurses
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- Morikawa Yuko
- Department of Public Health, Kanazawa Medical University
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- Kitaoka-Higashiguchi Kazuyo
- Department of Nursing, Ishikawa Prefectural Nursing University
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- Tanimoto Chie
- Department of Nursing, Ishikawa Prefectural Nursing University
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- Hayashi Midori
- Department of Nursing, Ishikawa Prefectural Nursing University
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- Oketani Reiko
- Department of Nursing, Ishikawa Prefectural Takamatsu Hospital
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- Miura Katsuyuki
- Department of Public Health, Kanazawa Medical University
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- Nishijo Muneko
- Department of Public Health, Kanazawa Medical University
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- Nakagawa Hideaki
- Department of Public Health, Kanazawa Medical University
書誌事項
- タイトル別名
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- A Cross-Sectional Study on the Relationship of Job Stress with Natural Killer Cell Activity and Natural Killer Cell Subsets among Healthy Nurses
- Cross Sectional Study on the Relationship of Job Stress with Natural Killer Cell Activity and Natural Killer Cell Subsets among Healthy Nurses
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抄録
The present study investigated the effects of job stress on cellular immune function, such as NK cell activity and NK cell subsets. The participants were 61 female nurses aged 23-59, who worked in a public psychiatric hospital in Ishikawa, Japan. Each subject completed the Nursing Job Stressor Scale (NJSS) and their NK cell activity and lymphocyte surface antigens (CD16+56+) were evaluated as immune system parameters. The NJSS has seven subscales: conflict with other nursing staff, nursing role conflict, conflict with physicians or autonomy, conflict with death or dying, quantitative work load, qualitative work load and conflict with patients. Factors influencing NK cell activity, and the proportion and cell counts of CD16+56+ lymphocytes were evaluated. Increase in quantitative work load significantly decreased NK cell activity. Conversely, no linear relationship was observed between qualitative work load and immunological variables, with the highest percentage of CD16+56+ lymphocytes observed among participants in the medium work load group. The other five NJSS subscales did not relate to immune parameters. In conclusion, the results suggest that perceived job strains, particularly quantitative work load, decreased NK cell function.<br>
収録刊行物
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- journal of Occupational Health
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journal of Occupational Health 47 (5), 378-383, 2005
公益社団法人 日本産業衛生学会
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詳細情報 詳細情報について
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- CRID
- 1390282679433517952
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- NII論文ID
- 110004018343
- 130004447299
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- NII書誌ID
- AA11090645
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- COI
- 1:STN:280:DC%2BD2MrlsVGisA%3D%3D
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- ISSN
- 13489585
- 13419145
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- NDL書誌ID
- 7462347
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- PubMed
- 16230830
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可