力学的複合要因を考慮した動脈瘤の成長シミュレーション(S02-1 生体組織のマルチスコープメカニクス(1).モデリングとメカニクス,S02 生体組織のマルチスコープメカニクス)

• 和田 成生

  東北大

• FENG Yixiang

  東北大

• 坪田 健一

  東北大

書誌事項

タイトル別名

• Computational analysis of the growth of aneurysm caused by multiple mechanical factors

抄録

Hemodynamics stresses are known to be able to degenerate the arterial wall and be involved in the pathogenesis of aneurysm formation and development. The present study numerically simulates the formation and growth of an aneurysm arising from a curved artery focusing on the interplay between the wall shear stress, arterial wall degeneration and deformation. It was hypothesized that if the local wall shear stress is higher than a threshold value, the Young's modulus of the wall is decreasedat'a fixed rate. The computer simulations clearly show the relationship among the change in the shape of the blood vessel, distribution of wall shear stress, and the degeneration of vessel wall during the progression of aneurysm, providing us new insight into the mechanism of aneurysm formation and development.

収録刊行物

• 年次大会講演論文集

  年次大会講演論文集 2004.5 (0), 3-4, 2004

  一般社団法人 日本機械学会

キーワード

• Computational Biomechanics
• Blood flow
• Deformation
• Material Properties
• Aneurysm
• Wall Shear Stress

詳細情報

• CRID: 1390001206059900160
• NII論文ID: 110004063732
• DOI: 10.1299/jsmemecjo.2004.5.0_3
• ISSN: 24331325
• Web Site: https://www.jstage.jst.go.jp/article/jsmemecjo/2004.5/0/2004.5_3/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可