中央に欠損を作成した膝蓋腱治癒組織の力学的特性に及ぼす加齢の影響(S04-2 医療とバイオエンジニアリング,工学技術の医療応用(2),S04 医療とバイオエンジニアリング,工学技術の医療応用)

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  • Effects of aging on the mechanical properties of the rabbit healing patellar tendon after removal of the central third

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The central third of the patellar tendon is a common substitute for anterior cruciate ligament reconstruction. Previous studies have shown that the mechanical strength of the tissue regenerated in the central defect of the patellar tendon increased with time, but that the strength of surrounding, residual tendon tissue decreased, followed by progressive recovery. However, effects of aging on the mechanical properties of such healing tissues remain unknown. In the present study, we investigated this issue using the patellar tendon of age-different rabbits: 2 and 3 months, and 2 years. Tensile tests were carried out at 3 and 4 weeks (2- and 3-month old), and 6 and 12 weeks (2-year-old) after the resection of the central portion. The mechanical properties of regenerated tissues seemed to be better at higher ages, and the recovery of residual tissues was delayed with age.

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