胸部大動脈瘤の発症・進展に伴う壁せん断応力の変化(J06-4 イメージベースト達成バイオメカニクス解析(4),J06 イメージベースト達成バイオメカニクス解析)

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  • Change in wall shear stress by initiation and growth of the aortic aneurysm

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The aortic arch is characterized by its configuration, large diameter and strong bend, and torsion in the arterial system. These characteristics induce the complex blood flow in the aorta, therefore leading to the distribution of the wall shear stress (WSS). The exact cause of the aneurysm is not known. However, it is reported that the aneurysm are most likely to occur at the site where the WSS is relatively high. So we propose that the initiation and growth of aortic aneurysm is related to WSS distribution. In this study, we analyzed flow in aortic arch various models with development of aortic aneurysm using computational fluid dynamics simulation. The result showed that the distortion of the aortic arch strongly influences WSS distribution, which is suspected to be related to the development of the aortic aneurysms.

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