Histoculture Drug Response Assay for Identifying Effective Anticancer Agents for Oral Squamous Cell Carcinoma: Report of Two Cases

• Ariyoshi Yasunori

  Departments of Oral Surgery, Osaka Medical College

• Shimahara Masashi

  Departments of Oral Surgery, Osaka Medical College

• Tanigawa Nobuhiko

  Departments of General and Gastroenterological Surgery, Osaka Medical College

• Tsuji Motomu

  Department of Surgical Pathology, Osaka Medical College Hospital

Abstract

Two cases of unresectable squamous cell carcinoma of the oral cavity were treated with combination chemotherapy using drugs determined to be effective in histoculture drug response assay with MTT end point. Both cases showed good response to the chemotherapy. The present results suggest that chemosensitivity testing facilitates individualization of chemotherapy.

Journal

• International Journal of Oral-Medical Sciences

  International Journal of Oral-Medical Sciences 2 (1), 44-49, 2004

  Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo

Keywords

• histoculture drug response assay
• MTT assay
• mouth neoplasm
• squamous cell carcinoma

Details

• CRID: 1390282680189750912
• NII Article ID: 110004313867
• NII Book ID: AA11830559
• DOI: 10.5466/ijoms.2.44
• ISSN: 21854254
• ISSN: 13479733
• Web Site: http://www.jstage.jst.go.jp/article/ijoms/2/1/2_1_44/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2004269333
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed