Polyclonal increases of serum immunoglobulins and increase of immunoglobulin-bearing peripheral blood lymphocytes in children with Kawasaki Disease

2 Citations
  • KUNO-SAKAI H
    Department of Pediatrics, School of Medicine, Tokai University
  • OHTA Tohru
    Department of Pediatrics, School of Medicine, Tokai University
  • KIKUCHI Toshiko
    Department of Pediatrics, School of Medicine, Tokai University
  • HIKINO Noriko
    Department of Pediatrics, School of Medicine, Tokai University
  • TAKESUE Ryozo
    Department of Pediatrics, School of Medicine, Tokai University
  • IWAGAKI Hiroyuki
    Department of Pediatrics, School of Medicine, Tokai University
  • TAKAKURA Iwao
    Department of Pediatrics, School of Medicine, Tokai University
  • KIMURA Mikio
    Department of Pediatrics, School of Medicine, Tokai University

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Abstract

Immunoglobulin-bearing peripheral blood lymphocytes were examined in 20 children with Kawasaki disease and in 13 healthy control children. Routine laboratory tests were also performed. IgG-bearing lymphocytes, IgA-bearing lymphocytes, and IgM-bearing lymphocytes increased in children with Kawasaki disease when compared with those of controls. Measurement of immunoglobulin-bearing cells in peripheral blood may be used as a clinical test in the diagnosis of Kawasaki disease.

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