An fMRI-MEG Integrative Method for Dynamic Imaging of Multiple Cortical Activities

• INNAMI Yasuyuki

  Faculty of Engineering, Graduate School of Kyoto University

• KOBAYASHI Tetsuo

  Faculty of Engineering, Graduate School of Kyoto University

• JUNG Jiuk

  Faculty of Engineering, Graduate School of Kyoto University

• OHASHI Shunpei

  Faculty of Engineering, Graduate School of Kyoto University

• HAMADA Shoji

  Faculty of Engineering, Graduate School of Kyoto University

• NAGAMINE Takashi

  Kyoto University Graduate School of Medicine

• FUKUYAMA Hidenao

  Kyoto University Graduate School of Medicine

• AZUMA Takashi

  Institute for Frontier Medical Sciences, Kyoto University

• TSUTSUMI Sadami

  Institute for Frontier Medical Sciences, Kyoto University

Bibliographic Information

Other Title

• 複数皮質活動の動的イメージングのためのfMRI-MEG統合解析法
• フクスウ ヒシツ カツドウ ノ ドウテキ イメージング ノ タメ ノ fMRI MEG トウゴウ カイセキホウ

Abstract

We have developed an fMRI-MEG integrative method that is capable of analyzing spatiotemporal multiple cortical activities. Firstly, activated regions were determined by statistically analyzing fMRI data. Secondly, using fMRI analysis results as a spatial constraint, the location and orientation of equivalent current dipoles (ECD) were estimated by a procedure that maximizes the inner product of lead field and measured field vectors. The time-varying dipole moment was obtained by projecting the optimized lead field vector to measured fields. We applied the technique to data obtained during a visual perception task. An apparent motion stimulus that activates both primary and secondary visual areas (V1/2) and V5 was used in the experiment. Event-related neuromagnetic fields were measured by a 306-channel MEG system, whereas the fMRI data were acquired by a 1.5 T MR system. The present fMRI-MEG integrative analysis method successfully detected dynamic cortical activities in V1/2 and V5.

Journal

• Transactions of Japanese Society for Medical and Biological Engineering

  Transactions of Japanese Society for Medical and Biological Engineering 43 (4), 777-784, 2005

  Japanese Society for Medical and Biological Engineering

Keywords

• fMRI-MEG integration
• dynamic imaging
• visual cortex

Details

• CRID: 1390282680244654976
• NII Article ID: 130004493975
• NII Article ID: 110004704995
• NII Book ID: AA11633569
• DOI: 10.11239/jsmbe.43.777
• ISSN: 18814379
• ISSN: 1347443X
• NDL BIB ID: 7886685
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7886685
• Web Site: https://search.jamas.or.jp/link/ui/2006156920
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed