Remarkable Solvent Effects on Depletion Interaction in Crowding Media: Analyses Using the Integral Equation Theories
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- Akiyama Ryo
- Department of Chemistry, Graduate School of Science, Kyushu University
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- Karino Yasuhito
- Department of Chemistry, Graduate School of Science, Kyushu University
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- Hagiwara Yasuhiro
- Department of Chemistry, Graduate School of Science, Kyushu University
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- Kinoshita Masahiro
- Institute of Advanced Energy, Kyoto University
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Abstract
In theoretical studies on the depletion interaction between macromolecules in crowding media, usually only the macromolecules and large cosolutes are considered by assuming that the solvent can be treated as an inert background. Here, the interaction between macromolecules immersed in a solvent–cosolute mixture is calculated using the integral equation theories combined with a hard-sphere model. On the basis of the results, we point out the crucial importance of explicit incorporation of solvent molecules in the theoretical treatment. The behavior observed is highly nonlinear due to the complicated intermolecular correlations and remarkably dependent on the total packing fraction and the cosolute concentration. An example result is that the cosolute can act both as a stabilizer and as a destabilizer for a dimer of macromolecules. We present new physical pictures elucidating the behavior.
Journal
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- Journal of the Physical Society of Japan
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Journal of the Physical Society of Japan 75 (6), 064804-, 2006
THE PHYSICAL SOCIETY OF JAPAN
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Details 詳細情報について
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- CRID
- 1390001204190508032
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- NII Article ID
- 110004731523
- 210000106206
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- NII Book ID
- AA00704814
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- BIBCODE
- 2006JPSJ...75f4804A
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- ISSN
- 13474073
- 00319015
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- NDL BIB ID
- 7941454
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed