Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma: A Case Report

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  • Yoshida Takashi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Koibuchi Yukio
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Horiguchi Jun
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Iijima Kotaro
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Kikuchi Mami
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Takata Daisuke
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Rokutanda Nana
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Nagaoka Rin
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Sato Ayako
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Oyama Tetsunari
    Department of Pathology, Dokkyo Medical University School of Medicine
  • Iino Yuichi
    Department of Emergency Medicine, Gunma University Graduate School of Medicine
  • Morishita Yasuo
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine

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We present a rare case of a 26-year old woman with diffuse sclerosing variant of papillary thyroid carcinoma. The patient was referred to our hospital with diffuse enlargement of the thyroid accompanied with palpable bilateral cervical lymph nodes. Ultrasonography showed a heterogeneous pattern with ill-defined hypoechoic areas in both thyroid lobes. There were multiple small punctate echogenic foci. Fine-needle aspiration cytology revealed typical signs of papillary carcinoma. The patient underwent a total thyroidectomy using a bilateral modified neck dissection. Pathological findings demonstrated diffuse involvement and continuous infiltration of the tumors to both thyroid lobes, lymph nodes and cervical soft tissue. Postoperatively, 100 mCi of 131I was administrated to the small amount of residual thyroid tissue. The patient is free from recurrence one year after the operation.

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