Isolation of Lawsonia intracellularis in Korea and Reproduction of Proliferative Enteropathy in Pigs and Hamsters

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  • YEH Jung-Yong
    National Veterinary Research and Quarantine Service
  • KIM Tae-Jong
    Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University
  • PARK Seung-Yong
    Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University
  • SONG Chang-Seon
    Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University
  • YOON Yong-Dhuk
    Green Cross Veterinary Institute, Green Cross Veterinary Product. Co., Ltd.
  • KIM Soo-Ki
    Institute of Biomedical Science and Technology, Konkuk University
  • LEE Joong-Bok
    Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University Institute of Biomedical Science and Technology, Konkuk University
  • CHOI In-Soo
    Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University Institute of Biomedical Science and Technology, Konkuk University

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Lawsonia intracellularis (L. intracellularis) was isolated from a Korean pig suffering acute proliferative enteropathy. In vitro culture conditions of L. intracellularis were established in McCoy cells. Pigs and hamsters experimentally infected with the pure culture of L. intracellularis reproduced clinical signs and intestinal lesions of proliferative enteropathy. The presence of L. intracellularis in the intestinal lesions was confirmed by immunohistochemistry with L. intracellularis-specific monoclonal antibodies.<br>

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