DNA塩基配列の統計力学的尺度を用いた生物進化の解析

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タイトル別名
  • Criterion of Evolution Analyzing DNA Sequences based on Statistical Mechanics
  • DNA エンキ ハイレツ ノ トウケイ リキガクテキ シャクド オ モチイタ セイブツ シンカ ノ カイセキ

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ABSTRACT Eukaryotic genes are composed of exons and introns. The former are translated into protein, but the latter are not. All the functions of introns are not necessarily clear. However, introns are believed to have close relations to the evolution of species, therefore to analyze introns is of great importance. To reveal hidden properties in introns, the concept of energy is extended and the extended energy is estimated based on Boltzmann distribution that is equivalent to the conditional probability. To compare the extended energy with that of other species tells the extended energy increases as the elapse time of evolutionary branches. The experiments lead us to the conclusion that the extended energy is a promising criterion to distinguish if there exists of common characteristics of species that have a common ancestor.

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