Clinical Usefulness of Antibodies against Babesia gibsoni Detected by ELISA with Recombinant P50

  • MIYAMA Takako
    Faculty of Agriculture, Yamaguchi University
  • INOKUMA Hisashi
    Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • ITAMOTO Kazuhito
    Faculty of Agriculture, Yamaguchi University
  • OKUDA Masaru
    Faculty of Agriculture, Yamaguchi University
  • VERDIDA Rodolfo A.
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
  • XUAN Xuenan
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine

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  • Babesia gibsoni組換えP50-ELISAで検出される抗体の臨床的有用性

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Abstract

The clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50 was examined in dogs in an area where B. gibsoni infection was endemic. Only 8 among 14 dogs with acute type B. gibsoni infection without a previous history of infection were positive. This high percentage of false-negative results is thought to be a weak point of ELISA as a diagnostic tool. However, 14 other anemic dogs with a confirmed history of B. gibsoni infection were all positive, thus confirming the higher sensitivity of ELISA in detecting a history of infection.<br>

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