Neurocysticercosis as Solitary Parenchymal Lesion Confirmed by Mitochondrial Deoxyribonucleic Acid Sequence Analysis-Case Report-

• ISHIKAWA Eiichi

  Department of Neurosurgery, Ibaraki Prefectural Central Hospital Department of Neurosurgery, Tsukuba Medical Center Hospital

• KOMATSU Yoji

  Department of Neurosurgery, Tsukuba Medical Center Hospital

• KIKUCHI Kazunori

  Department of Pathology, Tsukuba Medical Center Hospital

• YAMASAKI Hiroshi

  Department of Parasitology, Asahikawa Medical College

• KIMURA Hiroshi

  Department of Neurosurgery, Tsukuba Medical Center Hospital

• OSUKA Satoru

  Department of Neurosurgery, Tsukuba Medical Center Hospital

• TSURUBUCHI Takao

  Department of Neurosurgery, Tsukuba Medical Center Hospital

• ITO Akira

  Department of Parasitology, Asahikawa Medical College

• MATSUMURA Akira

  Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba

Bibliographic Information

Other Title

• —Case Report—

Abstract

A 38-year-old Japanese woman presented with neurocysticercosis manifesting as mild hemiparesis. Magnetic resonance (MR) imaging with gadolinium showed a solitary parenchymal lesion. MR spectroscopy of the mass showed a relatively low N-acetylaspartate peak. Enzyme-linked immunosorbent assay of the patient’s cerebrospinal fluid using antibodies against several parasite antigens was negative. Surgical resection of the lesion was performed. The histological findings showed the possibility of parasitic infection such as neurocysticercosis, although the definitive type of parasite was not confirmed. Sequencing of cytochrome c oxidase subunit 1 gene of mitochondrial deoxyribonucleic acid indicated the Asian genotype of Taenia solium. We propose that these new diagnostic techniques should be used more widely, especially for solitary lesions of neurocysticercosis.<br>

Journal

• Neurologia medico-chirurgica

  Neurologia medico-chirurgica 47 (1), 40-44, 2007

  The Japan Neurosurgical Society

Keywords

• intracranial granuloma
• neurocysticercosis
• magnetic resonance spectroscopy
• mitochondrial deoxyribonucleic acid sequence
• parenchymal solitary lesion

Details

• CRID: 1390001205052825216
• NII Article ID: 110006153455
• NII Book ID: AN00358613
• DOI: 10.2176/nmc.47.40
• COI: 1:STN:280:DC%2BD2s%2FksFGgsA%3D%3D
• ISSN: 13498029
• ISSN: 04708105
• Web Site: http://www.jstage.jst.go.jp/article/nmc/47/1/47_1_40/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007175353
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed