New Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861

• Bunyapaiboonsri Taridaporn

  National Center for Genetic Engineering and Biotechnology (BIOTEC)

• Yoiprommarat Seangaroon

  National Center for Genetic Engineering and Biotechnology (BIOTEC)

• Intereya Kamolphan

  National Center for Genetic Engineering and Biotechnology (BIOTEC)

• Kocharin Kanokarn

  National Center for Genetic Engineering and Biotechnology (BIOTEC)

抄録

Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A—C (1—3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861. Structures of these compounds were elucidated by NMR and MS spectral analyses. Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC₅₀ value of 1.3 μg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC₅₀ values of 8.65 and 3.72 μg/ml, respectively. Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 μg/ml.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 55 (2), 304-307, 2007

  公益社団法人 日本薬学会

キーワード

• <i>Cordyceps</i> sp.
• diphenyl ether
• phenyl ether glycoside

詳細情報

• CRID: 1390282679145986432
• NII論文ID: 110006162442
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.55.304
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 8616174
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8616174
• Web Site: http://www.jstage.jst.go.jp/article/cpb/55/2/55_2_304/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007192396
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可