ワルファリン抵抗性と感受性クマネズミに対するジフェチアロン製剤の効力  [in Japanese] Effectiveness of difethialone baits to warfarin-resistant and susceptible colonies of roof rats, Rattus rattus in Japan  [in Japanese]

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Author(s)

    • 石塚 真由美 ISHIZUKA Mayumi
    • 北海道大学大学院獣医学研究科毒性学教室 Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University
    • 藤田 正一 FUJITA Shoichi
    • 北海道大学大学院獣医学研究科毒性学教室 Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University

Abstract

The efficacy of toxic bait, which includes 0.0025% difethialone: [(bromo-4'-[biphenyl-1-1']-yl-4)3-tetrahydro-1,2,3,4-naphthyl-1] 3-hydroxy-4 2H-1 benzothiopyrane-one, was tested against warfarin-resistant and susceptible roof rats (Rattus rattus). When 0.0025% difethialone baits were given to the warfarinresistant roof rats, 5 of 12 warfarin-resistant rats were killed after eating a.i. (active ingredient) 1.8mg/kg in average for 24 hours. After eating 4.7mg/kg bait in average for 2 days, 11 of 12 rats were killed. Nine of 12 rats were killed 3 days after eating a.i. 6.9mg/kg. All rats tested died within 4 days after eating a.i. 10.4mg/kg (n=12). On the other hand, when 0.0025% difethialone baits were given to the warfarin-susceptible roof rats (n=12), all rats were killed after eating a.i. 1.7mg/kg in average for 24 hours exposure.

Journal

  • Medical Entomology and Zoology

    Medical Entomology and Zoology 57(4), 355-359, 2006

    The Japan Society of Medical Entomology and Zoology

References:  12

Cited by:  2

Codes

  • NII Article ID (NAID)
    110006197525
  • NII NACSIS-CAT ID (NCID)
    AN00021948
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0424-7086
  • NDL Article ID
    8656599
  • NDL Source Classification
    ZS17(科学技術--医学--衛生学・公衆衛生)
  • NDL Call No.
    Z19-47
  • Data Source
    CJP  CJPref  NDL  NII-ELS  J-STAGE 
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