Characteristics of Sleep Apnea-hypopnea Syndrome (SAHS) in Elderly Inpatients in a Long-term Care Facility

• Liu Wei Min.

  Department of Geriatric Medicine, Kanazawa Medical University Respiratory Department of Zhong Nan Hospital, Wu Han University

• Morimoto Shigeto

  Department of Geriatric Medicine, Kanazawa Medical University

• Okaishi Kohya

  Department of Geriatric Medicine, Kanazawa Medical University Department of Internal Medicine, Sengi-Hospital

• Matsumoto Masayuki

  Department of Geriatric Medicine, Kanazawa Medical University

抄録

OBJECTIVES: Sleep apnea-hypopnea syndrome (SAHS) in middle-aged subjects has been well characterized. The majority of SAHS presents as obstructive SAHS (OSAHS). It occurs more often in men, and is associated with cerebro-cardiovascular disease and its risk factors. Although numerous studies have suggested that the prevalence of SAHS is high in the elderly, its precise characteristics are not known. The aim of this study was to investigate the prevalence of SAHS in Japanese elderly inpatients in a hospital for the elderly, and to evaluate its characteristics. METHODS: The study was conducted in Japanese elderly inpatients aged 65 years or older with an admission period of 6 months or longer. The total study subjects consisted of 38 men and 107 women. After screening by pulse oximetry, SAHS patients were diagnosed (apnea-hypopnea index: AHI≥5/h) and classified into subtypes by polysomnography. RESULTS: We identified 46 SAHS patients (12 male and 34 female) out of the 145 subjects. However, there was no significant difference in the characteristics of SAHS, including prevalence (32% each), mean age (79 and 81 years old), and severity [mild/moderate/severe: 5 (13.2%)/6 (15.8%)/1 (2.6%) and 12 (11.2%)/13 (12.1%)/9 (8.4%)], between men and women. On the other hand, polysomnographic examination revealed an apparent predominance of mixed SAHS (MSAHS: 54%) and Cheyne-Stokes breathing syndrome (CSBS: 26%) rather than OSAHS (20%). Well-known factors associated with OSAHS such as hypertension, ischemic heart disease and cerebro-cardiovascular disease and with CSBS such as congestive heart failure in middle-aged subjects showed no significant association with SAHS as a whole or with any subtype of SAHS in the elderly compared to control elderly subjects. CONCLUSION: Compared to SAHS in middle-aged subjects, SAHS in elderly inpatients was characterized by a high prevalence, predominance of MSAHS and CSBS rather than OSAHS, and absence of association with well-known cerebro-cardiovascular factors. The pathogenesis of SAHS in elderly inpatients should be further clarified in the future.

収録刊行物

• 金沢医科大学雑誌

  金沢医科大学雑誌 30 (3), 155-160, 2005-10

  金沢医科大学

キーワード

• sleep apnea-hypopnea syndrome
• elderly
• obstructive sleep apnea-hypopnea syndrome
• Cheyne-Stokes breathing syndrome
• mixed sleep apnea-hypopnea syndrome

詳細情報

• CRID: 1571980077217830656
• NII論文ID: 110006198428
• NII書誌ID: AN00043827
• ISSN: 03855759
• 本文言語コード: en
• データソース種別:
  • CiNii Articles