Atherosclerotic Plaque Characterization by 0.5-mm-Slice Multislice Computed Tomographic Imaging Comparison With Intravascular Ultrasound

• Motoyama Sadako

  Department of Cardiology, Fujita Health University

• Kondo Takeshi

  Department of Cardiology, Takase Clinic

• Anno Hirofumi

  Department of Radiology, Fujita Health University

• Sugiura Atsushi

  Department of Cardiology, Fujita Health University

• Ito Yoshihiro

  Department of Cardiology, Fujita Health University

• Mori Kazumasa

  Department of Cardiology, Fujita Health University

• Ishii Junichi

  Department of Cardiology, Fujita Health University

• Sato Takahisa

  Department of Cardiology, Fujita Health University

• Inoue Kaori

  Department of Cardiology, Fujita Health University

• Sarai Masayoshi

  Department of Cardiology, Fujita Health University

• Hishida Hitoshi

  Department of Cardiology, Takase Clinic

• Narula Jagat

  Division of Cardiology, Department of Medicine, University of California at Irvine

Bibliographic Information

Other Title

• Atherosclerotic plaque characterization by 0.5-mm-slice multislice computed tomographic imaging
• Comparison With Intravascular Ultrasound

Abstract

Background It has been proposed that 0.5-mm-slice multislice computed tomography (MSCT) is a noninvasive tool for the detection of atherosclerotic plaque, but the validity of such an assessment has not been demonstrated by an invasive investigation. The present study was performed to compare the 0.5-mm-slice MSCT density of plaques with intravascular ultrasound (IVUS) findings. Methods and Results Atherosclerotic plaques were characterized in 37 consecutive patients undergoing percutaneous interventions. Based on the IVUS echogenecity, the plaques were classified as soft (n=18), fibrous (n=40) or calcified (n=40). In these 98 plaques, 0.5-mm-slice MSCT plaque density was calculated in 443 regions-of-interest, including 331 lesional foci and 112 luminal cross-sections, and represented as Hounsfield units (HU). MSCT density of the 3 types of plaque was 11±12 HU, 78±21 HU, and 516 ±198 HU respectively. Computed tomography density of the (contrast-filled) lumen was 258±43 HU. There were statistically highly significant differences in the densitometric characteristics among the 4 groups (soft, fibrous, calcified plaque and lumen) by nonparametric Kruskal-Wallis test (p<0.0001). Conclusions The IVUS-based coronary plaque configuration can be accurately identified by 0.5-mm slice MSCT. Noninvasive assessment of plaque characterization will ensure emphasis on the vessel wall beyond the vascular lumen. (Circ J 2007; 71: 363 - 366)<br>

Journal

• Circulation Journal

  Circulation Journal 71 (3), 363-366, 2007

  The Japanese Circulation Society

Keywords

• Computed tomography
• Coronary artery
• Intravascular ultrasound
• Plaque characterization

Details

• CRID: 1390282680082534528
• NII Article ID: 110006224205
• NII Book ID: AA11591968
• DOI: 10.1253/circj.71.363
• COI: 1:STN:280:DC%2BD2s7it1Ckuw%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• ISSN: http://id.crossref.org/issn/13469843
• PubMed: 17322636
• Web Site: http://www.jstage.jst.go.jp/article/circj/71/3/71_3_363/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007232688
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed