Histological Evaluation of Apatite Cement Containing Atelocollagen

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Author(s)

    • TAKECHI Masaaki
    • Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University
    • MIYAMOTO Youji
    • Division of Dentistry and Oral Surgery, Akita University Hospital
    • ISHIKAWA Kunio
    • Department of Biomaterials, Faculty of Dental Science, Kyushu University
    • MOMOTA Yukihiro
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
    • YUASA Tetsuya
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
    • TATEHARA Seiko
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
    • TAKANO Hideyuki
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
    • MINAMIGUCHI Shiho
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
    • NAGAYAMA Masaru
    • Department of Oral and Maxillofacial Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School

Abstract

Tissue response to apatite cement (AC) containing atelocollagen (AC (ate)) was evaluated using conventional AC (c-AC) as a control material. At one week, the only difference between AC (ate) and c-AC was found in the soft tissue response. With c-AC, a moderate inflammatory response was exhibited: small particles of c-AC were scattered in the cutaneous tissue and many foreign body giant cells were aggregated around the scattered c-AC, whereas AC (ate) showed only a slight inflammatory response with few foreign body giant cells. In terms of bone tissue response, difference between AC (ate) and c-AC was observed at four weeks. New bone formation was observed along the cement at the edge of the pre-existing cortical bone in both c-AC and AC (ate). However, in the case of AC (ate), more abundant and thicker new bone was formed along the cement in the bone marrow when compared with c-AC.

Journal

  • Dental Materials Journal

    Dental Materials Journal 26(2), 194-200, 2007-06-01

    The Japanese Society for Dental Materials and Devices

References:  72

Cited by:  1

Codes

  • NII Article ID (NAID)
    110006248845
  • NII NACSIS-CAT ID (NCID)
    AA10443149
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    02874547
  • Data Source
    CJP  CJPref  NII-ELS  J-STAGE  NDL-Digital 
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