Relationship Between Coronary Artery Remodeling and Plaque Composition in Culprit Lesions An Intravascular Ultrasound Radiofrequency Analysis
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- Higashikuni Yasutomi
- Division of Cardiology, Mitsui Memorial Hospital
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- Tanabe Kengo
- Division of Cardiology, Mitsui Memorial Hospital
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- Yamamoto Hirosada
- Division of Cardiology, Mitsui Memorial Hospital
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- Aoki Jiro
- Division of Cardiology, Mitsui Memorial Hospital
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- Nakazawa Gaku
- Division of Cardiology, Mitsui Memorial Hospital
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- Onuma Yoshinobu
- Division of Cardiology, Mitsui Memorial Hospital
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- Otsuki Shuji
- Division of Cardiology, Mitsui Memorial Hospital
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- Yagishita Atsuhiko
- Division of Cardiology, Mitsui Memorial Hospital
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- Yachi Sen
- Division of Cardiology, Mitsui Memorial Hospital
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- Nakajima Hiroyoshi
- Division of Cardiology, Mitsui Memorial Hospital
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- Hara Kazuhiro
- Division of Cardiology, Mitsui Memorial Hospital
書誌事項
- タイトル別名
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- An Intravascular Ultrasound Radiofrequency Analysis
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Background The relationship between coronary artery remodeling and culprit plaque composition in vivo has not been fully evaluated by spectral analysis of intravascular ultrasound (IVUS) radiofrequency (RF) data. Methods and Results IVUS RF analyses were performed for 56 consecutive de novo culprit lesions of 52 patients undergoing percutaneous coronary intervention. Remodeling of culprit lesions was determined using the remodeling index (RI), calculated as the external elastic membrane area of the minimum lumen area (MLA) site divided by that of the proximal reference site. Positive remodeling was defined as RI >1.05, intermediate remodeling as 0.95≤ RI ≤1.05 and negative remodeling as RI <0.95. Among the 56 lesions, positive remodeling was detected in 24, intermediate remodeling in 16, and negative remodeling in 16. At MLA sites, positive remodeling lesions had a larger percentage of the fibrofatty component than negative remodeling lesions (22.5±10.3% vs 10.4±6.6%, p=0.0001), whereas the latter contained a larger percentage of the dense calcium component than the former (2.8±2.9% vs 8.4±7.0%, p=0.016). Conclusions Culprit plaques with positive remodeling have a large lipid burden, whereas those with negative remodeling contain a large amount of calcium. (Circ J 2007; 71: 654 - 660)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 71 (5), 654-660, 2007
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205104868608
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- NII論文ID
- 110006273598
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
- http://id.crossref.org/issn/13469843
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可