超大量化学療法を施行した脾血管肉腫の1例

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  • A Case of Hemangiosarcoma of the Spleen in which Supermass Chemotherapy was Successfully Performed

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A 48-year-old woman reporting left hypochondriac pain, together with anemia and thrombocytopenia identified elsewhere, was found on palpation to have hard elastic masses in the left upper quadrant. Blood tests confirmed anemia and thrombocytopenia. Computed tomography (CT) showed partially contrasting nonuniform internal tumors corresponding to the spleen. FDG-PET indicated an accumulation from the left upper quadrant to the flank. Because thrombocytopenia had been worsened by blood transfusion and platelet transfusions, we initially diagnosed as pancytopenia due to hypersplenism, necessitating splenectomy. The extracted 15×12×12cm specimen weighted, 990g, had a smooth surface, and was hard and elastic. The cut surface was solid. Histopathological examination indicated hemangiosarcoma. After surgery, she was treated with supermass chemotherapy and peripheral blood stem cell transplantation. As of this writing 3 years after surgery, she continues to do well with no signs of recurrence.

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