茶花(チャ, Camellia sinensis, 花蕾部)の機能性サポニン : Floratheasaponin 類の胃保護作用と血糖値上昇抑制作用及びHPLCを用いた定性及び定量分析  [in Japanese] Functional Saponins in Tea Flower (Flower Buds of Camellia sinensis) : Gastroprotective and Hypoglycemic Effects of Floratheasaponins and Qualitative and Quantitative Analysis Using HPLC  [in Japanese]

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Author(s)

Abstract

  As a part of our characterization studies on the bioactive saponin constituents of tea flowers (<i>Camellia sinensis</i>, flower buds), the methanolic extract and 1-butanol-soluble portion (the saponin fraction) from the flower buds were found to exhibit potent inhibitory effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats and on serum glucose elevation in sucrose-loaded rats. Among the constituents of the 1-butanol-soluble portion, floratheasaponins A, B, and C showed gastroprotective and hypoglycemic activities. Furthermore, we have developed qualitative and quantitative methods using HPLC for the principle saponins, floratheasaponins A-F, in tea flowers, which were previously found to show antiallergic and antiobesity effects. Using those methods, the saponin composition of Indian tea flowers were found to be similar to those of Chinese (Anhui) but not of Japanese tea flowers. On the other hand, it was found that the floratheasaponin contents in tea flowers varied markedly during the blooming period, and they were abundant at half-bloom. Additionally, the contents of caffeine in the tea flowers were examined using HPLC.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 128(1), 141-151, 2008-01-01

    The Pharmaceutical Society of Japan

References:  43

Cited by:  3

Codes

  • NII Article ID (NAID)
    110006533013
  • NII NACSIS-CAT ID (NCID)
    AN00284903
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    00316903
  • NDL Article ID
    9334671
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-411
  • Data Source
    CJP  CJPref  NDL  NII-ELS  J-STAGE 
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