Heavy-Ion Microbeam System at JAEA-Takasaki for Microbeam Biology
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- FUNAYAMA Tomoo
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- WADA Seiichi
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- YOKOTA Yuichiro
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- FUKAMOTO Kana
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- SAKASHITA Tetsuya
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- TAGUCHI Mitsumasa
- Organic Pollutant Removal Technology Group, Japan Atomic Energy Agency
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- KAKIZAKI Takehiko
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency
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- HAMADA Nobuyuki
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency Department of Quantum Biology, and The 21st Century Center of Excellence (COE) Program, Gunma University Graduate School of Medicine
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- SUZUKI Michiyo
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency Japan Society for the Promotion of Science
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- FURUSAWA Yoshiya
- Heavy-ion Radiobiology Research Group, National Institute of Radiological Sciences
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- WATANABE Hiroshi
- Radia Industry Co., Ltd
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- KIGUCHI Kenji
- Department of Applied Biology, Faculty of Textile Science and Technology, Shinshu University
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- KOBAYASHI Yasuhiko
- Microbeam Radiation Biology Group, Japan Atomic Energy Agency Department of Quantum Biology, and The 21st Century Center of Excellence (COE) Program, Gunma University Graduate School of Medicine
Bibliographic Information
- Other Title
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- Heavy-ion microbeam system in JAEA for microbeam biology
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Abstract
Research concerning cellular responses to low dose irradiation, radiation-induced bystander effects, and the biological track structure of charged particles has recently received particular attention in the field of radiation biology. Target irradiation employing a microbeam represents a useful means of advancing this research by obviating some of the disadvantages associated with the conventional irradiation strategies. The heavy-ion microbeam system at JAEA-Takasaki, which was planned in 1987 and started in the early 1990's, can provide target irradiation of heavy charged particles to biological material at atmospheric pressure using a minimum beam size 5 μm in diameter. A variety of biological material has been irradiated using this microbeam system including cultured mammalian and higher plant cells, isolated fibers of mouse skeletal muscle, silkworm (Bombyx mori) embryos and larvae, Arabidopsis thaliana roots, and the nematode Caenorhabditis elegans. The system can be applied to the investigation of mechanisms within biological organisms not only in the context of radiation biology, but also in the fields of general biology such as physiology, developmental biology and neurobiology, and should help to establish and contribute to the field of "microbeam biology".
Journal
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- Journal of Radiation Research
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Journal of Radiation Research 49 (1), 71-82, 2008
Journal of Radiation Research Editorial Committee
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Keywords
Details 詳細情報について
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- CRID
- 1390001205215359488
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- NII Article ID
- 110006570530
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- NII Book ID
- AA00705792
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- COI
- 1:STN:280:DC%2BD1c%2FnvFOjtQ%3D%3D
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- ISSN
- 13499157
- 04493060
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- NDL BIB ID
- 9350473
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- PubMed
- 18174669
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- NDL-Digital
- CiNii Articles
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- Abstract License Flag
- Disallowed