Panduratins D-I, Novel Secondary Metabolites from Rhizomes of Boesenbergia pandurata

• Win Nwet Nwet

  Institute of Natural Medicine, University of Toyama

• Awale Suresh

  Institute of Natural Medicine, University of Toyama

• Esumi Hiroyasu

  National Cancer Center Research Institute East

• Tezuka Yasuhiro

  Institute of Natural Medicine, University of Toyama

• Kadota Shigetoshi

  Institute of Natural Medicine, University of Toyama

抄録

Investigation of the non-polar fraction of Boesenbergia pandurata of Myanmar led to the identification of six novel secondary metabolites, panduratins D—I (1—6), together with known diastereomers, panduratins B1 (7) and B2 (8). Their structures were determined based on extensive spectroscopic analysis. The in vitro preferential cytotoxicity of all isolates was examined against human pancreatic PANC-1 cancer cells under nutrient-deprived conditions. All exhibited a mild activity.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 56 (4), 491-496, 2008

  公益社団法人 日本薬学会

キーワード

• <i>Boesenbergia pandurata</i>
• secondary metabolite
• preferential cytotoxicity
• PANC-1

詳細情報

• CRID: 1390282679146579584
• NII論文ID: 110006649351
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.56.491
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 9432819
• Web Site: http://id.ndl.go.jp/bib/9432819
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9432819
• Web Site: http://www.jstage.jst.go.jp/article/cpb/56/4/56_4_491/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可