中毒性表皮壊死症(TEN)に対する血漿交換療法(<特集>皮膚疾患とアフェレシス)

NDLデジタルコレクション 被引用文献1件

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  • Plasmapheresis for the Treatment of Toxic Epidermal Necrolysis

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Toxic epidermal necrolysis (TEN) is one of the serious drug eruptions with a high mortality rate. TEN also may cause severe consequences such as visual or respiratory disorders. Therefore, immediate diagnosis and initiation of correct therapy are most important. Apheresis therapy including plasma exchange for the treatment of TEN has been approved by the National Health Insurance System in Japan from 2006, due to the accumulation of successfully treated TEN patients with apheresis. In this study, we summarized the TEN patients treated with apheresis in our country, and discussed the timing to recruit the apheresis, as well as the mechanisms of apheresis. These examinations will provide an insight into a more appropriate treatment modality for the patients with TEN.

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