チワワにおいて認められた顆粒細胞様変化を有する髄膜腫の1例

  • TAKEUCHI Yoshinori
    Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • OHNISHI Yumi
    Department of Veterinary Clinical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • MATSUNAGA Satoru
    Department of Veterinary Clinical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • NAKAYAMA Hiroyuki
    Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • UETSUKA Koji
    Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo

書誌事項

タイトル別名
  • Intracranial Meningioma with Polygonal Granular Cell Appearance in a Chihuahua
  • Pathology: Intracranial meningioma with polygonal granular cell appearance in a Chihuahua

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抄録

A menigioma with polygonal granular cell proliferation in an 11-year and 8-month-old male Chihuahua is described. The tumor was observed under the dura matter of the right cerebrum. Microscopically, the tumor consisted of solid growth foci of small- or large- sized polygonal cells, with pale-stained nuclei, prominent nucleoli, and fine granular to foamy eosinophilic cytoplasm. Some of the proliferating cells contained variable amounts of cytoplasmic PAS-positive granules. Immunohistochemical analysis revealed that neoplastic cells were positive for vimentin and S-100 protein. Ultrastructurally, the neoplastic cells contained vesicular structures with a few small round-shaped bodies in the cytoplasm. We diagnosed the case as canine meningioma with granular cell appearance.<br>

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