Decreased Renal Function as an Independent Predictor of Re-Hospitalization for Congestive Heart Failure

  • Komukai Kimiaki
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Ogawa Takayuki
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Yagi Hidenori
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Date Taro
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Sakamoto Hiroshi
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Kanzaki Yasuko
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Shibayama Kenri
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Hashimoto Koichi
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Inada Keiichi
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Minai Kosuke
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Ogawa Kazuo
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Kosuga Tsuneharu
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Kawai Makoto
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Hongo Kenichi
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Taniguchi Ikuo
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
  • Yoshimura Michihiro
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

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Background Patients with congestive heart failure (CHF) are often re-hospitalized, worsening both their quality of life and prognosis. Although renal dysfunction reportedly increases the risk of CHF, the association between renal dysfunction and re-hospitalization for CHF remains unclear. Methods and Results Patients with CHF and decreased renal function were reviewed. The estimated glomerular filtration rate (GFR) was calculated with the Modification of Diet in Renal Disease equation. Patients with decreased renal function (estimated GFR on admission <45 ml ·min-1 · 1.73 m-2) were re-hospitalized more frequently than were patients with preserved renal function (estimated GFR on admission ≥45). Patients with decreased renal function were older and had higher rates of anemia, worsening renal function during hospitalization, and previous hospitalization for CHF. Independent predictors of re-hospitalization for CHF identified with multivariate analysis were age, previous hospitalization for CHF, decreased renal function, and non-use of an angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker. Conclusions Renal dysfunction is an independent predictor of re-hospitalization for CHF, so careful follow-up is needed, even after discharge. (Circ J 2008; 72: 1152 - 1157)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 72 (7), 1152-1157, 2008

    一般社団法人 日本循環器学会

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