A CASE OF SYSTEMIC LUPUS ERYTHEMATOSUS OCCURRED AFTER INDUCED ABORTION AND DRUG ERUPTION
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- Sasaki Nobuhito
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Baba Shunu
- Department of dermatology, Iwate Medical University
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- Takahashi Susumu
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Itou Harumasa
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Kowada Kouko
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Shikanai Toshiki
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Nakamura Yutaka
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Yamauchi Kohei
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Inoue Hiroshi
- 3^<rd> Department of Internal Medicine, Iwate Medical University
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- Sawai Takashi
- Department of Pathology, Iwate Medical University
Bibliographic Information
- Other Title
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- 人工流産および薬疹後に全身性エリテマトーデスが発症した1例
- 症例報告 人工流産および薬疹後に全身性エリテマトーデスが発症した1例
- ショウレイ ホウコク ジンコウ リュウザン オヨビ ヤクシンゴ ニ ゼンシンセイ エリテマトーデス ガ ハッショウシタ 1レイ
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Abstract
We describe a19 year-old woman who was diagnosed as systemic lupus erythematosus (SLE) after abortion. She had taken anti-convulsants for epilepsy since she was 8 years old. Induced abortion surgery was performed at six weeks in her pregnancy. She showed pyrexia and a general rash 2 days after the abortion. She was introduced to our hospital because the administration of antibiotics was not effective. Since the anti-convulsants had been changed after pregnancy, we returned to those administered before pregnancy and followed her up. Her eruption improved, but she became aware of thirstiness and dry eye. She was diagnosed as Sjogren syndrome by ophthalmologic examination, lip biopsy, and elevation of an anti-SS-A antibody and an anti-SS-B antibody in the serum. Since we could not rule out SLE because of the low concentration of complement activity in blood, we followed her up carefully by checking serum markers of SLE. Protein urine developed after the improvement of the eruption 2 weeks later. Low complement activity was recognized and double stranded (ds)-DNA antibody became positive. In addition to these findings, she had an episode of hypersensitivity to sunlight and was therefore diagnosed as SLE. Since induced abortion and drug eruption might be associated with the onset of SLE, the case is thought to be a valuable from the view point of understanding the mechanism of SLE onset.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 57 (7), 872-877, 2008
Japanese Society of Allergology
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Details 詳細情報について
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- CRID
- 1390282679967100416
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- NII Article ID
- 110006862976
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 9620070
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed