Demographics and Changes in Medical/Interventional Treatment of Coronary Artery Disease Patients Over a 3.5-Year Period in Japan The Japanese Coronary Artery Disease Study: Trend Examination

• Kohro Takahide

  Department of Translational Research for Healthcare and Clinical Science, Graduate School of Medicine, The University of Tokyo

• Hayashi Doubun

  Department of Translational Research for Healthcare and Clinical Science, Graduate School of Medicine, The University of Tokyo

• Okada Yoshihiro

  Department of Translational Research for Healthcare and Clinical Science, Graduate School of Medicine, The University of Tokyo

• Yamazaki Tsutomu

  Department of Clinical Epidemiology & Systems, Graduate School of Medicine, The University of Tokyo

• Nagai Ryozo

  Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo

• The JCAD Investigators

書誌事項

タイトル別名

• The Japanese Coronary Artery Disease Study: Trend Examination

抄録

Background Cardiovascular medicine has undergone rapid changes in recent years, but there are insufficient reports using large cohorts regarding these changes for Japanese coronary artery disease (CAD) patients. Hence, a large-scale prospective observational study was needed. Methods and Results A total of 36,298 patients were registered over 6 periods. Patients with hypertension, hyperlipidemia, obesity, and impaired glucose tolerance increased in number, while those with old myocardial infarction (MI), smoking habit, and family history of CAD decreased. Regarding the trends in interventional procedures, stent use increased in both the whole cohort and the acute MI subgroup, while the use of only medical control decreased. Regarding prescription trends, angiotensin-receptor blockers increased while nitrates decreased. Conclusions In a period of 3.5 years, significant changes were observed for both interventional procedures and medication, which might be related to the well-timed compliance of physicians with published evidence. However, these changes were not related to changes in the event rates, at least over the short term. Although careful attention should be paid in interpreting the results, because this is an observational study and the background of patients in each cohort might have been heterogeneous, such investigations should be constantly conducted for evidence-based practice. (Circ J 2008; 72: 1397 - 1402)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 72 (9), 1397-1402, 2008

  一般社団法人 日本循環器学会

キーワード

• Coronary artery disease
• Evidence-based practice
• Medicine
• Percutaneous intervention
• Trends

詳細情報

• CRID: 1390282680078502400
• NII論文ID: 110006894371
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-08-0140
• ISSN: 13474820
• ISSN: 13469843
• Web Site: http://www.jstage.jst.go.jp/article/circj/72/9/72_CJ-08-0140/_pdf
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
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