Parasitology: Developmental stage- and organ-specific expression profiles of asparaginyl endopeptidases/legumains in the ixodid tick Haemaphysalis longicornis
-
- ALIM M. Abdul
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- TSUJI Naotoshi
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- MIYOSHI Takeharu
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- ISLAM M. Khyrul
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- HATTA Takeshi
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- YAMAJI Kayoko
- Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural and Food Research Organization
-
- FUJISAKI Kozo
- National Research Centre for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine Laboratory of Emerging Infectious Diseases, School of Frontier Veterinary Medicine, Kagoshima University
書誌事項
- タイトル別名
-
- Developmental Stage- and Organ-Specific Expression Profiles of Asparaginyl Endopeptidases/Legumains in the Ixodid Tick Haemaphysalis longicornis
この論文をさがす
抄録
We previously identified two cDNAs from the midgut of adult Haemaphysalis longicornis that encode asparaginyl endopeptidases/legumains, HlLgm and HlLgm2. Functionally, both recombinant HlLgm and HlLgm2 efficiently digested blood proteins, haemoglobin and bovine serum albumin. Here, we investigated the expression profiles of legumain genes in the developmental stages in the life cycle of H. longicornis and in different tissues of adult ticks. Both HlLgm and HlLgm2 were well expressed in larvae, nymphs and adults. Legumain transcripts were expressed specifically in the midgut and were localized in some digestive vacuoles of gut epithelial cells. Furthermore, expression of either transcript was up-regulated by blood feeding in larvae and nymphs, suggesting the important roles of legumains in blood feeding and blood-meal digestion in ticks.<br>
収録刊行物
-
- The Journal of Veterinary Medical Science
-
The Journal of Veterinary Medical Science 70 (12), 1363-1366, 2008
公益社団法人 日本獣医学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001206429096704
-
- NII論文ID
- 110007021720
-
- NII書誌ID
- AA10796138
-
- ISSN
- 13477439
- 09167250
-
- NDL書誌ID
- 9760402
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可