ADVOCATING THE DIAGNOSTIC CRITERIA FOR EARLY STAGE OF ASTHMA

• Sugiyama Kumiya

  Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University

• Sagara Hironori

  Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University

• Adachi Mitsuru

  Department of Medicine, Showa University School of Medicine

• Minoguchi Kenji

  Department of Medicine, Showa University School of Medicine

• Tanaka Akihiko

  Department of Medicine, Showa University School of Medicine

• Inoue Hiroshi

  Division of Pulmonary Medicine, Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine

• Yamauchi Kouhei

  Division of Pulmonary Medicine, Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine

• Kobayashi Hitoshi

  Division of Pulmonary Medicine, Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine

• Akiyama Kazuo

  Clinical Research Center for Allergy and Rheumatology, National Hospital Orgnization, Sagamihara National Hospital

• Tsurikisawa Naomi

  Clinical Research Center for Allergy and Rheumatology, National Hospital Orgnization, Sagamihara National Hospital

• Taniguchi Masami

  Clinical Research Center for Allergy and Rheumatology, National Hospital Orgnization, Sagamihara National Hospital

• Munakata Mitsuru

  Department of Pulmonary Medicine, Fukushima Medical University

• Saito Junpei

  Department of Pulmonary Medicine, Fukushima Medical University

• Sato Suguru

  Department of Pulmonary Medicine, Fukushima Medical University

• Mishima Michiaki

  Department of Respiratory Medicine, Kyoto University

• Niimi Akio

  Department of Respiratory Medicine, Kyoto University

• Matsumoto Hisako

  Department of Respiratory Medicine, Kyoto University

• Ohta Ken

  Department of Medicine, Teikyo University School of Medicine

• Adachi Tetsuya

  Department of Medicine, Teikyo University School of Medicine

• Nagase Hiroyuki

  Department of Medicine, Teikyo University School of Medicine

• Nakajima Hiroshi

  Department of Molecular Genetics, Chiba University

• Kagami Shin-ichiro

  Department of Allergy and Clinical Immunology, Chiba University

• Iwamoto Itsuo

  Research Center for Allergy and Clinical Immunology, Asahi General Hospital

• Fukuda Takeshi

  Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University

Bibliographic Information

Other Title

• 気管支喘息の早期診断基準の提言
• キカンシ ゼンソク ノ ソウキ シンダン キジュン ノ テイゲン

Abstract

Background: In asthmatic patients, first asthmatic symptoms are not often typical. In those cases, it takes long time before asthma diagnosis, and the severities are progressed in some patients. For early intervention, we tried to make the diagnostic criteria for asthma, which are useful to diagnose as early stage of asthma. Methods: Three hundred and eighty eight of asthmatic patients, who were recorded first their symptoms in asthma, were enrolled. Their first symptoms and examinations were analyzed. Results: In first asthmatic symptoms, 79% of patients had cough, 68% patients had wheezing, 49% patients had dyspnoea, and 15% of patients did not have typical asthmatic symptoms in the early stage. The percentages of abnormal in first examinations were 99% in airway hypersensitivity, 92% of low %V_<25>, 82% of eosinophila in sputum and 77% of low %V_<50>. Low FEV_<1%> and reversible airway obstruction were not seen in a lot of patients. Conclusion: We advocate that the diagnostic criteria for early stage of asthma are the following three elements. First criterion is spasmodic cough, wheezing and dyspnoea. Second criterion is airway hypersensitivity, or over 3% of eosinophils in sputum, or under 70% of %V_<50>, or under 50% of %V_<25>, or effect of bronchodilator. Effect of bronchodilator will be required, when the symptom is cough only. Third criterion is the exclusion of other lung and heart diseases.

Journal

• Japanese Journal of Allergology

  Japanese Journal of Allergology 57 (12), 1275-1283, 2008

  Japanese Society of Allergology

Keywords

• asthma
• diagnostic criteria
• early diagnosis

Details

• CRID: 1390282679967165952
• NII Article ID: 110007043580
• NII Book ID: AN00012583
• DOI: 10.15036/arerugi.57.1275_1
• ISSN: 13477935
• ISSN: 00214884
• NDL BIB ID: 10158605
• Web Site: http://id.ndl.go.jp/bib/10158605
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10158605
• Web Site: https://search.jamas.or.jp/link/ui/2009126079
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed