A case report of chemotherapy resistant Stage IV Wilms tumor, favorable histology

• Takagi,Masatoshi

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Aoki,Yuki

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Isoda,Takeshi

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Sato,Ryusuke

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School:Department of Pediatrics, Tokyo Kita Social Insurance Hospital

• Mitsuiki,Noriko

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Kajiwara,Michiko

  Department of Blood Transfusion, Tokyo Medical and Dental University

• Nagasawa,Masayuki

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Morio,Tomohiro

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

• Lee,Kyeong Deok

  Department of Pediatric General and Urogenital Surgery, Juntendo University, School of Medicine

• Yamataka,Atsuyuki

  Department of Pediatric General and Urogenital Surgery, Juntendo University, School of Medicine

• Morikawa,Nobuyuki

  Division of General Surgery, National Center for Child Medical Health and Development

• Kuroda,Tatsuo

  Division of General Surgery, National Center for Child Medical Health and Development

• Mizutani,Shuki

  Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School

Bibliographic Information

Other Title

• 化学療法抵抗性を示したWilms腫瘍,favorable histology,ステージIVの1例

Abstract

We have experienced a Stage IV Wilms tumor patient. The tumor was chemotherapy resistant although the pathological specimen showed favorable histology. Surgical resection was performed for a lung metastatic lesion after several cycles of chemotherapy. Pathological examination revealed that most of the metastatic nephroblastic cells carried differentiation potency. Complete remission was achieved after high dose chemotherapy with peripheral stem cell support followed by surgery, and the patient has remained in remission for more than 12 months. This case provide a information on the treatment strategy for a relapsed Wilms tumor with the favorable histology.

Journal

• 小児がん : 小児悪性腫瘍研究会記録

  小児がん : 小児悪性腫瘍研究会記録 46 (3), 387-392, 2009-09-25

  がんの子供を守る会

Keywords

• Nephroblastoma
• Wilms Tumor
• Chemotherapy
• differentiation
• surgical approach

Details

• CRID: 1540291245381217920
• NII Article ID: 110007359111
• NII Book ID: AN00116159
• Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10755253
• Web Site: https://search.jamas.or.jp/link/ui/2009340564
• Text Lang: ja
• Data Source:
  • NDL-Digital
  • CiNii Articles
  • KAKEN