DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise

  • Hashimoto Kazunori
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Honda Akiko
    Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University
  • Hayashi Yuichi
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Inuzuka Takashi
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Satoh Masahiko
    Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University
  • Hozumi Isao
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine

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抄録

We present herein transcriptional changes in mouse spinal cords in response to physical exercise on a treadmill using a DNA microarray. By 30-min exercise, the expression of 3 genes was enhanced and expression of 29 genes reduced. By continuous 2-week exercise (30-min exercise per day), the expression of 1 gene was enhanced and expression of 13 genes reduced.

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