咽頭上気道細菌に対する精油及びオレオレジンの抗菌活性 Antibacterial Activity of Essential Oils and Oleoresins of Spices and Herbs against Pathogens Bacteria in Upper Airway Respiratory Tract

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Author(s)

    • 菊崎 泰枝 Kikuzaki Hiroe
    • 大阪市立大学大学院生活科学研究科食・健康科学講座 Division of Food and Health Sciences, Graduate School of Human Life Science, Osaka City University
    • 中谷 延二 Nakatani Nobuji
    • 大阪市立大学大学院生活科学研究科食・健康科学講座 Division of Food and Health Sciences, Graduate School of Human Life Science, Osaka City University

Abstract

精油50種類及びオレオレジン24種類について咽頭上気道細菌、<i>Streptococcus pyogenes</i>、<i>Haemophilus influenzae</i>、<i>Moraxella catarrhalis</i>に対する抗菌試験を行った。精油の中ではシナモンリーフ、セージ、クローブ、カルダモン、タイムに効果がみられ、オレオレジンではイチョウ、甘草、ナツメグに抗菌性が見られた。さらに代表的な精油成分より45種の揮発性化合物を選択し抗菌活性を調べた。精油成分の中ではcarvacrol、methyl chavicol、bornyl acetate、menthyl acetate、α-terpinyl acetate、viridiflorolに効果がみられた。カルダモン、ローレル、メリッサ精油と同様に3種の主要な成分geranyl acetate, menthyl acetate, α-terpinyl acetateは上気道微生物に対して有効な抗菌性成分となり得ることが示唆された。抗菌活性を示したシナモンリーフ油およびクローブ油の主成分eugenolは単独ではほとんど活性が認められなかったが、β-Caryophylleneに対してeugenolは優れた相乗効果を示すことが認められた。

The antibacterial activity of 50 essential oils and 24 oleoresins of spices and herbs against upper airway respiratory tract bacteria such as <i>Streptococcus pyogenes</i>, <i>Haemophilus influenzae</i>, and <i>Moraxella catarrhalis</i> was examined. The essential oils of cinnamon leaf, sage, clove, cardamom and thyme, and the oleoresins of ginkgo, licorice and nutmeg inhibited the growth of the bacteria. The antimicrobial test was also carried out on selected 45 volatile chemical compounds. Among the selected volatile constituents, carvacrol, methyl chavicol, bornyl acetate, menthyl acetate, α-terpinyl acetate and viridiflorol showed the antimicrobial effect. Essential oils of cardamom, laurel and melissa as well as three of their major constituents, geranyl acetate, menthyl acetate and α-terpinyl acetate, possessed antibacterial property against upper airway respiratory tract bacteria. Although eugenol, which was major compornent of cinnamon leaf and clove oils with antibacterial activity, did not show any activity against oropharyngeal pathogens, eugenol played a considerable synergistic effect on β-caryophyllene.

Journal

  • Japanese Journal of Food Chemistry and Safety

    Japanese Journal of Food Chemistry and Safety 9(2), 67-76, 2002

    Japanese Society of Food Chemistry

References:  32

Codes

  • NII Article ID (NAID)
    110007367250
  • NII NACSIS-CAT ID (NCID)
    AA11666400
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    1341-2094
  • NDL Article ID
    6339290
  • NDL Source Classification
    ZP34(科学技術--食品工学・工業)
  • NDL Call No.
    Z17-B99
  • Data Source
    CJP  NDL  NII-ELS  J-STAGE 
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