SPONTANEOUS MUSCLE WEAKNESS IN HIGH THYMOMA BUFFALO/MNA RATS

• 松山 睦司

  Laboratory of Ultrastructure Research, Aichi Cancer Center Research Institute

• 伊藤 一

  Laboratory of Ultrastructure Research, Aichi Cancer Center Research Institute

• 益山 芳正

  Department of Ophthalmology, Miyazaki University Medical School

• 中村 隆昭

  2nd Department of Pathology, Nagoya City University Medical School

• 飯田 光男

  1st Department of Medicine, Nagoya University Medical School

抄録

A majority of adult male rats of the high thymoma Buffalo/Mna strain showed myathenic signs: a lesser ability to remain on the revolving roller of a Rotor Load than rats of other strains and waning in the electromyograms of the gastrocnemius. Submicroscopical examination of the extraocular muscles indicated the elongation and ramification of the postsynaptic membrane of the motor end plates and moderate degeneration of the muscle cells. Treatment with the anticholinesterase, edrophonium chloride, dramatically alleviated the waning seen in electromyography.

収録刊行物

• Nagoya medical journal

  Nagoya medical journal 23 (2), 93-98, 1978-11-28

  名古屋市立大学

キーワード

• muscle weakness
• thymoma
• Rotor Load
• electromyogram
• electron microscopy of extraocular muscles

詳細情報

• CRID: 1570572702628437248
• NII論文ID: 110007506682
• NII書誌ID: AA00750902
• ISSN: 00277649
• Web Site: https://search.jamas.or.jp/link/ui/1981081954
• 本文言語コード: en
• データソース種別:
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