胎児発育および新生児出生体重に及ぼす妊婦の体重増加に関する研究  [in Japanese] Analysis of the relationship between the maternal weight gain and birth weight  [in Japanese]

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Abstract

背景:低出生体重児は将来的に生活習慣病を発症する頻度が高いことが指摘されている。一方,わが国では母親の低栄養状態との関連が示唆される低出生体重児の増加傾向が続いている。このため胎児発育にかかわる妊婦の体重管理の定量的な評価は重要な課題である。方法と結果:単胎妊婦33名を対象として,母親の体重変化を,母親実質体重増加量(子宮・皮下脂肪・循環血液増加量など).胎児体重,胎盤重量,羊水量に細分化し,胎児の発育に影響を及ぼす因子を検討した。母親の非妊時体重と非妊時BMIは,週あたりの児の体重増加量(非妊時体重:r=0.42,p<0.05,非妊時BMI:r=0.41,p<0.05),および週あたりの胸囲増加量と有意な正相関を示した。児の体重増加量は,週あたりの母親体重増加量と有意な関連を示さなかったが,週あたりの母親実質体重増加量と有意な正相関を示した(r=0.50,p<0.01)。結論:胎児発育は,妊娠前の母親の栄養状態,および妊娠中の母親白身の栄養状態を意味する実質体重増加に依存し,妊娠可能年齢女性の妊娠前からの栄養・体重管理と,妊娠中の母親の十分な栄養摂取に基づく代謝環境の形成は,良好な胎児の発育のために極めて重要である。

Background: The number of low-birth weight infants (LBW<2,500g), presumably due to maternal under-nutrition, has recently increased in Japan. However, precisely how maternal weigh gain should be controlled in order to obtain both optimal fetal growth and birth weight still remains to be elucidated. Method: On 33 pregnant women with a single birth, the relationship between the fetal growth and maternal body weight (MBW) was herein studied by dividing the MBW into 4 components, including substantial MBW (including the uterus, adipose tissues, blood and so on), fetal weight, amniotic fluid and placenta. Results: Based on the findings of partial correlation coefficient analyses, the pre-pregnant maternal BMI (r=0.42, p<0.5) and MBW (r=0.41, p<0.05) were found to be significantly proportional to the fetal weight per week as well as the gain in chest circumference per week (p<0.05). The substantial MBW gain per week was also significantly associated with the fetal weight gain per week (r=0.05, p<0.01), despite the absence of any correlation between the total MBW gain per week and the fetal weight gain per week. Conclusion: Fetal growth was therefore found to be strongly affected by the pre-pregnant MBW and the substantial MBW gain during pregnancy. Given the disease risk that are associated with environmental influences in early life, the nutritional status of females during childbearing age and gestation is thus considered to be quite important to obtain an optimal reproductive outcome.

Journal

  • Japanese journal of maternal health.

    Japanese journal of maternal health. 51(1), 92-98, 2010-04-01

    Japan Society of Maternal Health

References:  20

Cited by:  1

Codes

  • NII Article ID (NAID)
    110007609823
  • NII NACSIS-CAT ID (NCID)
    AN0022863X
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03881512
  • NDL Article ID
    10662284
  • NDL Source Classification
    ZS38(科学技術--医学--産婦人科学) // ZE5(社会・労働--社会問題・社会保障)
  • NDL Call No.
    Z19-1016
  • Data Source
    CJP  CJPref  NDL  NII-ELS 
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