Relationship between Severity of Coronary Artery Stenosis and of Calcificaton and CKD : Comparisons of CT Coronary Angiography with eGFR in Patients with Cardiovascular Disease

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  • Relationship between severity of coronary artery stenosis and of calcification and CKD comparisons of CT coronary angiography with eGFR in patients with cardiovascular disease

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To investigate the relationship between chronic kidney disease (CKD) and the severity of coronary artery stenosis and of calcification, we compared estimated glomerular filtration rates (eGFR) with coronary stenosis and coronary artery calcification scores (CACS) assessed by CT coronary angiography in 300 patients (146 men, 154 women ; average age, 68.8 y). Among these, 275 assessable patients were classified according to stenosis rates of <25%, 25-49%, 50-74% and .75% as normal coronary arteries (n=129) and slight (n=50), moderate (n=39) and severe (n=57) stenosis, respectively. They were also classified by total CACS of 0, 0.1-100, 101-399 and .400 as having non-calcification (n=93), slight (n=79), moderate (n=50) and severe calcification (n=53), respectively. The average (± standard deviation) eGFR values of the groups with normal arteries, slight, moderate and severe stenosis were 81.86±20.10, 76.29±19.51, 76.59±19.83 and 66.83 ± 17.75, respectively. Those of the groups with non-calcification, slight, moderate and severe calcification were 80.76±17.53, 79.46±23.06, 72.69±20.65 and 70.84±17.76, respectively. Our findings indicated that CKD might cause coronary stenosis and calcification to be severe.

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  • 秋田医学

    秋田医学 37 (2), 93-102, 2010-01-01

    秋田医学会

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