口底部に転移した肺癌の1例

  • 松本 直子
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野
  • 大橋 祐生
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野
  • 宮形 養
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野
  • 飯島 伸
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野
  • 星 秀樹
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野
  • 杉山 芳樹
    岩手医科大学歯学部口腔外科学講座歯科口腔外科学分野

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  • A case of lung carcinoma metastasizing to the oral floor

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Metastatic tumors of the oral region account for about 1-2% of all malignant neoplasms of the oral cavity, and have been reported to be often located in the jaw bone and gingiva, and rarely in the floor of the mouth. <br> Recently, we encountered an 80-year-old man with suspected metastatic lung cancer of the mouth floor. He visited our department with a chief complaint of a painless swelling on the right side involving the floor of the mouth on December 21, 2007. The initial examination revealed a 15×10-mm indurated mass on the right side of the mouth floor, and plain chest X-ray showed a shadow with irregular margins in the right lung lower lobe. PET-CT showed FDG uptake on the right side of the mouth floor with an SUV of 5.5 and in the right lung lower lobe with an SUV of 6.4. Biopsy of the lesions in the oral cavity and lung led to a diagnosis of adenocarcinoma. The histological features of the oral cavity lesion differed from those of primary adenocarcinoma of the oral cavity, and resembled those of the lung lesion. With a diagnosis of metastatic lung adenocarcinoma of the oral cavity, the patient received chemotherapy at the Department of Respiratory Medicine. However, the primary lesion enlarged, cerebral hemorrhage occurred during treatment, and he died of a deteriorated general condition in May 2008.

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