Modification Effect of Novel Phosphate-type Hybrid Surfactant on Hydroxyapatite

• MORI Rie

  Division of Restorative Dentistry, Department of Oral Medicine, Kanagawa Dental College

• NIHEI Tomotaro

  Division of Restorative Dentistry, Department of Oral Medicine, Kanagawa Dental College

• OHASHI Katsura

  Division of Restorative Dentistry, Department of Oral Medicine, Kanagawa Dental College

• KURATA Shigeaki

  Department of Biomaterials and Devices, Kanagawa Dental College

• KONDO Yukishige

  Department of Industrial Chemistry, Tokyo University of Science

• YOSHINO Norio

  Department of Industrial Chemistry, Tokyo University of Science

• TERANAKA Toshio

  Division of Restorative Dentistry, Department of Oral Medicine, Kanagawa Dental College

Bibliographic Information

Other Title

• ハイドロキシアパタイトに対する新規リン酸エステル塩型ハイブリッド界面活性剤の改質効果

Abstract

It has been suggested that reducing the surface free energy of the tooth surface may prevent plaque accumulation and reduce the incidence of caries and periodontal disease. We synthesized a novel aqueous hybrid surfactant that can be added to dentifrice, namely sodium phenyl 1-[(4-perfluorohexyl)phenyl]-1-hexylphosphate (F6H5OP), which is a molecule containing a long fluorocarbon chain, a hydrocarbon chain, and a phosphate ester. In this study, we investigated the reduction in surface free energy on a hydroxyapatite (HAP) pellet and the inhibition of the calcium binding protein, phosvitin, on HAP powder modified with F6H5OP The amount of F6H5OP adsorbed to the HAP powder was determined by high-performance liquid chromatography. The F6H5OP water solution was applied to HAP pellets with a microbrush. The specimens were stored in water for 3 and 12 hours at 37℃. The surface free energies of the modified specimens were calculated by measuring the surface contact angles of distilled water and diiodomethan. The amount of phosvitin adsorbed to the HAP powder was determined by gel permeation chromatography. The resistance to rinsing with deionized water and the inhibitory effect of phosvitin adsorption to HAP powder were also measured. More than 70% of F6H5OP in deionized water was adsorbed to the HAP powder within 5 minutes. The contact angles of the HAP pellets modified with F6H5OP were significantly higher than that of the non-treated control, and the surface free energies were significantly lower than that of the control after the 12-hour water immersion. The inhibition ratio of phosvitin adsorption to modified HAP powder following rinsing twice with deionized water was about 40% after immersion in water for 12 hours. These results suggest that the novel phosphate-type hybrid surfactant F6H5OP has a significant modification effect on the surface of hydroxyapatite.

Journal

• The Japanese Journal of Conservative Dentistry

  The Japanese Journal of Conservative Dentistry 53 (2), 182-190, 2010

  The Japanese Society of Conservative Dentistry

Keywords

• Surfactant
• Hydroxyapatite
• Modification effect

Details

• CRID: 1390282680497047168
• NII Article ID: 110007880724
• NII Book ID: AN00191201
• DOI: 10.11471/shikahozon.53.182
• ISSN: 21880808
• ISSN: 03872343
• Web Site: https://search.jamas.or.jp/link/ui/2010226864
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed