Improvement of spatial resolution by light guide array structure for in vivo fluorescent imaging

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  • ANDO Keisuke
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • KOBAYASHI Takuma
    Graduate School of Materials Science, Nara Institute of Science and Technology:CREST, Japan Science and Technology Agency (JST)
  • NODA Toshihiko
    Graduate School of Materials Science, Nara Institute of Science and Technology:CREST, Japan Science and Technology Agency (JST)
  • SASAGAWA Kiyotaka
    Graduate School of Materials Science, Nara Institute of Science and Technology:CREST, Japan Science and Technology Agency (JST)
  • TOKUDA Takashi
    Graduate School of Materials Science, Nara Institute of Science and Technology:CREST, Japan Science and Technology Agency (JST)
  • OHTA Jun
    Graduate School of Materials Science, Nara Institute of Science and Technology:CREST, Japan Science and Technology Agency (JST)

Bibliographic Information

Other Title
  • ライトガイドアレイ構造による生体蛍光イメージングの高空間分解能化(高機能イメージセンシングとその応用)
  • ポスター講演 ライトガイドアレイ構造による生体蛍光イメージングの高空間分解能化
  • ポスター コウエン ライトガイドアレイ コウゾウ ニ ヨル セイタイ ケイコウ イメージング ノ コウクウカン ブンカイ ノウゲ

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Abstract

Implantation of a CMOS image sensor into the brain of a living animal can realize neural activity imaging in a deep brain with high spatio-temporal resolution. We have successfully demonstrated that employing a light guide array structure on a sensor improves a spatial resolution, even if without any optics such as a micro lens array. Fluorescence imaging of a mouse brain slice is demonstrated by using the fabricated sensor.

Journal

  • ITE Technical Report

    ITE Technical Report 35.19 (0), 45-47, 2011

    The Institute of Image Information and Television Engineers

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