ローズマリー葉に含有される抗変異原性物質  [in Japanese] Antimutagens Involving in the Leaves of Rosmarinus officinalis L  [in Japanese]

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Author(s)

    • 中杉 徹 NAKASUGI TOHRU
    • 稲畑香料株式会社生薬研究部 Research Laboratory of Medicinal Products of Plant Origin, Inabata Koryo Co., Ltd.
    • 駒井 功一郎 KOMAI KOICHIRO
    • 近畿大学農学部農芸化学科農薬化学研究室 Laboratory of Pesticide Chemistry, Department of Agricultural Chemistry, Kinki University

Abstract

Antimutagenic activities of substances from Rosmarinus officinalis L. (rosemary) of the family Labiatae were investigated. A hot water extract prepared from rosemary leaves which had been steam distilled inhibited the frameshift mutation caused by 3-amino-l-methyl-5H-pyrido[4,3b]indole in Salmonella typhimurium TA98. Two active substances were identified in the hot water extract, which were 5-hydroxy-6,7,4'-trimethoxyflavone (salvigenin) and 5,4'-dihydroxy-6,7-dimethoxyflavone (cirsimaritin). These are the first flavones reported in rosemary leaves.

Journal

  • Natural Medicines

    Natural Medicines 50(5), 354-357, 1996-10-20

    日本生薬学会

References:  25

Codes

  • NII Article ID (NAID)
    110008731706
  • NII NACSIS-CAT ID (NCID)
    AN10438628
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    13403443
  • NDL Article ID
    4069705
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-375
  • Data Source
    CJP  NDL  NII-ELS  NDL-Digital 
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