ユーカリノキ (Eucalyptus globulus) の齲蝕原因菌に対する抗菌活性及びグルコシルトランスフェラーゼ阻害効果  [in Japanese] Antibacterial Activity of Eucalyptus globulus on Cariogenic Bacteria and its Inhibitory Effect on Glucosyltransferase  [in Japanese]

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Author(s)

Abstract

The leaves of Eucalyptus globulus contain unique macrocarpals consisting of a phrologlucinol and sesquiterpene having an antibacterial activity on oral bacteria and an inhibitory effect on glucosyltransferase (GTase). In this paper, a 60% ethanol extract of E. globulus leaves (extract A) and its EtOAc-soluble fraction (extract B) containing most of macrocarpals were examined for the cariostatic effects in vitro. The extracts A and B inhibited the growth of cariogenic bacteria at concentrations of 6.25-50 and 3.13-25 μg/ml, respectively, but their antibacterial activities on the intestinal bacteria were relatively low. The extracts A and B strongly inhibited the glucan synthesis, especially adhesive-insoluble glucan synthesis by GTase prepared from S. sobrinus 6715.

Journal

  • Natural Medicines

    Natural Medicines 52(1), 32-37, 1998-02-20

    日本生薬学会

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Codes

  • NII Article ID (NAID)
    110008731817
  • NII NACSIS-CAT ID (NCID)
    AN10438628
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    13403443
  • NDL Article ID
    4438499
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-375
  • Data Source
    CJP  CJPref  NDL  NII-ELS  NDL-Digital 
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