薬用植物中の酸化型エラジタンニン成分とその生理活性  [in Japanese] Oxidized Ellagitannins in Medicinal Plants and Their Biological Activities  [in Japanese]

Access this Article

Author(s)

    • 伊東 秀之 ITO Hideyuki
    • 岡山大学大学院自然科学研究科 Graduate School of Natural Science and Technology, Okayama University

Abstract

Geraniin and related dehydroellagitannins having a reactive dehydrohexahydroxydiphenoyl (DHHDP) group in the molecule have been widely found in the euphorbiaceous and geraniaceous plants. Further investigation on the polyphenols in Phyllanthus flexuosus, Acalypha hispida and Geranium thunbergii belonging to each family resulted in the isolation of eleven new analogues of geraniin and the characterization of their complex structures possessing a new highly oxidized acyl unit produced from the DHHDP group. New highly oxidized ellagitannins of other types, i.e., those having a gluconic acid core and C-glucosidic ellagitannin oligomers were also found in Elaeagnaceae and Fagaceae. Diverse biological properties including anti-ulcer and anti-tumor promoting effects, and antibacterial activity against Helicobacter pylori and antifungal activity were also exhibited by those highly oxidized ellagitannins.

Journal

  • Natural medicines

    Natural medicines 59(2), 57-62, 2005-04-20

    日本生薬学会

References:  21

Codes

  • NII Article ID (NAID)
    110008732360
  • NII NACSIS-CAT ID (NCID)
    AN10438628
  • Text Lang
    JPN
  • Article Type
    REV
  • ISSN
    13403443
  • NDL Article ID
    7328384
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-375
  • Data Source
    CJP  NDL  NII-ELS  NDL-Digital 
Page Top